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Saturday, September 23, 2006
Can a vitamin alleviate chronic, progressive multiple sclerosis? Ongoing nerve-fiber damage, disability prevented in animal study - Children's Hospital Boston, the primary pediatric teaching hospital of Harvard Medical School: " Researchers have found a possible way to protect people with multiple sclerosis (MS) from severe long-term disability: increase nervous-system levels of a vital compound, called nicotinamide adenine dinucleotide (NAD), by giving its chemical precursor.
Current therapies for MS mainly address the relapsing-remitting phase of the disease, but some of these have severe side effects, and most patients eventually enter a chronic progressive phase for which there is no good treatment. Using a mouse model of MS, researchers in the Neurobiology Program at Children's Hospital Boston found strong evidence that an inexpensive, readily available compound may protect against nerve damage in the chronic progressive phase, when the most serious disabilities occur. Their findings appear in a cover article in the September 20 Journal of Neuroscience......." |